Myositis autoantibodies and clinical phenotypes
نویسندگان
چکیده
منابع مشابه
Novel autoantibodies and clinical phenotypes in adult and juvenile myositis
Autoantibodies targeting intracellular proteins involved in key processes are detected in patients with idiopathic inflammatory myopathies. These myositis-specific autoantibodies have been increasingly demonstrated to correlate with distinct clinical phenotypes within the myositis spectrum. This review highlights the clinical associations of the myositis-specific autoantibodies, with particular...
متن کاملMyositis specific autoantibodies: changing insights in pathophysiology and clinical associations.
PURPOSE OF REVIEW Defined autoantibodies are found in about half of the patients with myositis. Traditionally, these autoantibodies have been divided into myositis specific autoantibodies (MSAs) and myositis associated autoantibodies. Several studies have shown that MSAs are associated with specific clinical characteristics and can aid our understanding of the pathophysiology of myositis. REC...
متن کاملsignificance of myositis - specific and myositis - associated autoantibodies
Autoantibodies to various cellular constituents are detected in the sera of patients with idiopathic inflammatory myopathy (IIM). These autoantibodies are closely associated with characteristic clinical manifestations of the diseases. Therefore, autoantibodies give us much information in clinical diagnosis, classification, prediction of prognosis and choice of treatment in patients with IIM. Du...
متن کاملClinical Usefulness of Autoantibodies in Idiopathic Inflammatory Myositis
One of the most important characteristics of systemic autoimmune diseases, including idiopathic inflammatory myopathies (IIM), is the immune response to self-antigens manifested by the production of autoantibodies that recognize a variety of cytoplasmic and nuclear antigens. In the last 40 years, autoantibodies of patients with IIM have been investigated; however, some of the fundamental questi...
متن کاملUpdate on myositis-specific and myositis-associated autoantibodies.
Myositis-specific autoantibodies or myositis-associated autoantibodies can often be found in serum of patients with polymyositis and dermatomyositis. The presence of these autoantibodies can be significant in patient diagnosis and classification. Recent studies have provided new information about many of these specific autoantibodies. Among the more important developments were identification of...
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ژورنال
عنوان ژورنال: Autoimmunity Highlights
سال: 2014
ISSN: 2038-0305,2038-3274
DOI: 10.1007/s13317-014-0060-4